article Open AccessTop 1% cited
The m 6 A Methyltransferase METTL3 Promotes Translation in Human Cancer Cells
Molecular Cell · 2016 · Vol. 62(3) · pp. 335–345
Shuibin Lin✉(Boston Children's Hospital)Junho Choe(Boston Children's Hospital)Peng Du(Boston Children's Hospital)Robinson Triboulet(Boston Children's Hospital)Richard I. Gregory(Boston Children's Hospital)
RNA modifications and cancerCancer-related gene regulationRNA Research and SplicingBiologyTranslation (biology)Cell biologyMessenger RNATranslational regulationRibosome biogenesisMethyltransferaseCancer researchRibosomeRNA
MeSH terms
A549 CellsAdenocarcinoma of LungTranscriptional Coactivator with PDZ-Binding Motif ProteinsAdenocarcinomaCell MovementCell SurvivalHumansLung NeoplasmsMethyltransferasesNeoplasm InvasivenessPeptide Chain Initiation, TranslationalRibosomesRNA, MessengerTranscription FactorsTransfection
Funding
- Damon Runyon Cancer Research Foundation
- National Institute of General Medical Sciences
Citations
1,617
FWCI
48.22
field-weighted impact
References
47
Percentile
100%
vs. same field & year
Citations per year
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References
m6A RNA Modification Controls Cell Fate Transition in Mammalian Embryonic Stem Cells
Cell stem cell · 2014 · 1,358 citations
N6-methyladenosine modification destabilizes developmental regulators in embryonic stem cells
Nature Cell Biology · 2014 · 1,318 citations
Perturbation of m6A Writers Reveals Two Distinct Classes of mRNA Methylation at Internal and 5′ Sites
Cell Reports · 2014 · 1,241 citations
ALKBH5 Is a Mammalian RNA Demethylase that Impacts RNA Metabolism and Mouse Fertility
Molecular Cell · 2012 · 3,616 citations
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