articleTop 1% cited
HBXIP-elevated methyltransferase METTL3 promotes the progression of breast cancer via inhibiting tumor suppressor let-7g
Cancer Letters · 2017 · Vol. 415 · pp. 11–19
Xiaoli Cai(Nankai University)Xiao Wang(Nankai University)Can Cao(Nankai University)Yuen Gao(Nankai University)Shuqin Zhang(Nankai University)Zhe Yang(Nankai University)Yunxia Liu(Nankai University)Xiaodong Zhang(Nankai University)Weiying Zhang✉(Nankai University)Lihong Ye✉(Nankai University)
RNA modifications and cancerCancer-related gene regulationEpigenetics and DNA MethylationSuppressorCancer researchBreast cancerMethyltransferaseChemistryInflammationTumor progressionMedicineCancerInternal medicine
MeSH terms
AdultAgedBase SequenceBreast NeoplasmsFemaleHumansMethyltransferasesMiddle AgedSequence Homology, Nucleic AcidGene Expression Regulation, NeoplasticGenes, Tumor SuppressorDisease Progression3' Untranslated RegionsMicroRNAsAdaptor Proteins, Signal Transducing
Funding
- National Natural Science Foundation of China
- National Key Research and Development Program of China
- Fundamental Research Funds for the Central Universities
Citations
491
FWCI
17.57
field-weighted impact
References
50
Percentile
100%
vs. same field & year
Citations per year
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References
Conserved Seed Pairing, Often Flanked by Adenosines, Indicates that Thousands of Human Genes are MicroRNA Targets
Cell · 2005 · 11,901 citations
Perturbation of m6A Writers Reveals Two Distinct Classes of mRNA Methylation at Internal and 5′ Sites
Cell Reports · 2014 · 1,241 citations
ALKBH5 Is a Mammalian RNA Demethylase that Impacts RNA Metabolism and Mouse Fertility
Molecular Cell · 2012 · 3,616 citations
The m 6 A Methyltransferase METTL3 Promotes Translation in Human Cancer Cells
Molecular Cell · 2016 · 1,617 citations
m 6 A Demethylase ALKBH5 Maintains Tumorigenicity of Glioblastoma Stem-like Cells by Sustaining FOXM1 Expression and Cell Proliferation Program
Cancer Cell · 2017 · 1,539 citations
m6A RNA Methylation Regulates the Self-Renewal and Tumorigenesis of Glioblastoma Stem Cells
Cell Reports · 2017 · 1,321 citations
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