articleTop 1% cited
N6-methyladenosine modification destabilizes developmental regulators in embryonic stem cells
Nature Cell Biology · 2014 · Vol. 16(2) · pp. 191–198
Yang Wang✉(Sanford Burnham Prebys Medical Discovery Institute)Yue Li(University of Toronto)Julia I. Toth(Sanford Burnham Prebys Medical Discovery Institute)Matthew D. Petroski(Sanford Burnham Prebys Medical Discovery Institute)Zhaolei Zhang(University of Toronto)Jing Zhao(Sanford Burnham Prebys Medical Discovery Institute)
RNA modifications and cancerCancer-related gene regulationCancer-related molecular mechanisms researchBiologyN6-MethyladenosineGene knockdownCell biologyEmbryonic stem cellMethyltransferaseMessenger RNAmicroRNAMethylationRNA
MeSH terms
AdenosineAmino Acid SequenceAnimalsCell LineHumansMethyltransferasesMolecular Sequence DataRNA, MessengerSequence Homology, Amino AcidGene Expression Regulation, DevelopmentalMiceEmbryonic Stem CellsGene Knockdown Techniques
Citations
1,318
FWCI
33.88
field-weighted impact
References
41
Percentile
100%
vs. same field & year
Citations per year
Cited by
YTHDC1 mediates nuclear export of N6-methyladenosine methylated mRNAs
eLife · 2017 · 1,219 citations
m6A RNA Methylation Regulates the Self-Renewal and Tumorigenesis of Glioblastoma Stem Cells
Cell Reports · 2017 · 1,321 citations
RNA N6‐methyladenosine methyltransferase‐like 3 promotes liver cancer progression through YTHDF2‐dependent posttranscriptional silencing of SOCS2
Hepatology · 2017 · 1,517 citations
Gene expression regulation mediated through reversible m6A RNA methylation
Nature Reviews Genetics · 2014 · 1,978 citations
m 6 A Demethylase ALKBH5 Maintains Tumorigenicity of Glioblastoma Stem-like Cells by Sustaining FOXM1 Expression and Cell Proliferation Program
Cancer Cell · 2017 · 1,539 citations
Nuclear m6A Reader YTHDC1 Regulates mRNA Splicing
Molecular Cell · 2016 · 2,096 citations
m6A RNA Modification Controls Cell Fate Transition in Mammalian Embryonic Stem Cells
Cell stem cell · 2014 · 1,358 citations
Perturbation of m6A Writers Reveals Two Distinct Classes of mRNA Methylation at Internal and 5′ Sites
Cell Reports · 2014 · 1,241 citations
References
Genomewide Analysis of PRC1 and PRC2 Occupancy Identifies Two Classes of Bivalent Domains
PLoS Genetics · 2008 · 995 citations
Integrative genomics viewer
Nature Biotechnology · 2011 · 16,203 citations
Mapping identifiers for the integration of genomic datasets with the R/Bioconductor package biomaRt
Nature Protocols · 2009 · 4,486 citations
TopHat: discovering splice junctions with RNA-Seq
Bioinformatics · 2009 · 12,093 citations
BEDTools: a flexible suite of utilities for comparing genomic features
Bioinformatics · 2010 · 29,774 citations
The Sequence Alignment/Map format and SAMtools
Bioinformatics · 2009 · 66,208 citations
Ultrafast and memory-efficient alignment of short DNA sequences to the human genome
Genome biology · 2009 · 22,766 citations
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
Proceedings of the National Academy of Sciences · 2005 · 55,472 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.