articleTop 1% cited
m 6 A Demethylase ALKBH5 Maintains Tumorigenicity of Glioblastoma Stem-like Cells by Sustaining FOXM1 Expression and Cell Proliferation Program
Cancer Cell · 2017 · Vol. 31(4) · pp. 591–606.e6
Sicong Zhang(The University of Texas Health Science Center at Houston)Boxuan Zhao(Howard Hughes Medical Institute)Aidong Zhou(The University of Texas MD Anderson Cancer Center)Kangyu Lin(The University of Texas MD Anderson Cancer Center)Shaoping Zheng(The University of Texas MD Anderson Cancer Center)Zhike Lu(Howard Hughes Medical Institute)Yaohui Chen(The University of Texas MD Anderson Cancer Center)Erik P. Sulman(The University of Texas MD Anderson Cancer Center)Keping Xie(The University of Texas MD Anderson Cancer Center)Oliver Bögler(The University of Texas MD Anderson Cancer Center)Sadhan Majumder(The University of Texas MD Anderson Cancer Center)Chuan He(University of Chicago)Suyun Huang✉(The University of Texas MD Anderson Cancer Center)
RNA modifications and cancerCancer-related molecular mechanisms researchRNA Research and SplicingBiologyDemethylaseFOXM1TranscriptomeGene silencingCarcinogenesisStem cellCancer researchCell biologyTranscription factor
MeSH terms
ELAV-Like Protein 1AlkB Homolog 5, RNA DemethylaseForkhead Box Protein M1AnimalsBrain NeoplasmsGlioblastomaMaleMice, NudeNeoplastic Stem CellsGene Expression Regulation, Neoplastic3' Untranslated RegionsXenograft Model Antitumor AssaysCell Line, TumorCell ProliferationGene Knockdown Techniques
Funding
- Howard Hughes Medical Institute
- National Institutes of Health
- University of Texas MD Anderson Cancer Center
Citations
1,539
FWCI
55.07
field-weighted impact
References
52
Percentile
100%
vs. same field & year
Citations per year
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References
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Cell stem cell · 2014 · 1,358 citations
N6-methyladenosine modification destabilizes developmental regulators in embryonic stem cells
Nature Cell Biology · 2014 · 1,318 citations
Hypoxia-Inducible Factors Regulate Tumorigenic Capacity of Glioma Stem Cells
Cancer Cell · 2009 · 1,308 citations
Identification of a CpG Island Methylator Phenotype that Defines a Distinct Subgroup of Glioma
Cancer Cell · 2010 · 2,346 citations
The Somatic Genomic Landscape of Glioblastoma
Cell · 2013 · 5,082 citations
TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions
Genome biology · 2013 · 13,586 citations
Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation
Nature Biotechnology · 2010 · 16,341 citations
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