review Open AccessTop 1% cited
The role of microglia and macrophages in glioma maintenance and progression
Nature Neuroscience · 2015 · Vol. 19(1) · pp. 20–27
Dolores Hambardzumyan(Cleveland Clinic Lerner College of Medicine)David H. Gutmann(Washington University in St. Louis)Helmut Kettenmann✉(Max Delbrück Center)
Neuroinflammation and Neurodegeneration MechanismsImmune cells in cancerGlioma Diagnosis and TreatmentMicrogliaNeuroscienceGliomaNeuroscientistBiologyPsychologyInflammationImmunologyCentral nervous systemCancer research
MeSH terms
AnimalsGliomaHumansMacrophagesCentral Nervous System NeoplasmsMicrogliaDisease Progression
Funding
- U.S. Department of Defense
- James S. McDonnell Foundation
- Cleveland Clinic
- National Cancer Institute
Citations
1,623
FWCI
39.61
field-weighted impact
References
97
Percentile
100%
vs. same field & year
Citations per year
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References
CSF-1R inhibition alters macrophage polarization and blocks glioma progression
Nature Medicine · 2013 · 2,418 citations
Local self-renewal can sustain CNS microglia maintenance and function throughout adult life
Nature Neuroscience · 2007 · 1,582 citations
PTEN/PI3K/Akt Pathway Regulates the Side Population Phenotype and ABCG2 Activity in Glioma Tumor Stem-like Cells
Cell stem cell · 2009 · 796 citations
Blood Monocytes Consist of Two Principal Subsets with Distinct Migratory Properties
Immunity · 2003 · 3,313 citations
Possible involvement of the M2 anti‐inflammatory macrophage phenotype in growth of human gliomas
The Journal of Pathology · 2008 · 728 citations
Monocyte recruitment during infection and inflammation
Nature reviews. Immunology · 2011 · 2,909 citations
Colony-Stimulating Factor 1 Receptor Signaling Is Necessary for Microglia Viability, Unmasking a Microglia Progenitor Cell in the Adult Brain
Neuron · 2014 · 1,980 citations
Fate Mapping Reveals Origins and Dynamics of Monocytes and Tissue Macrophages under Homeostasis
Immunity · 2012 · 3,222 citations
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