articleTop 1% cited
Local self-renewal can sustain CNS microglia maintenance and function throughout adult life
Nature Neuroscience · 2007 · Vol. 10(12) · pp. 1538–1543
Bahareh Ajami✉(University of British Columbia)Jami Bennett(University of British Columbia)Charles Krieger(Simon Fraser University)Wolfram Tetzlaff(University of British Columbia)Fábio Rossi(University of British Columbia)
Neuroinflammation and Neurodegeneration MechanismsNeurogenesis and neuroplasticity mechanismsAlzheimer's disease research and treatmentsMicrogliaParabiosisNeuroscienceProgenitor cellBiologyStem cellImmunologyInflammationCell biology
MeSH terms
AnimalsCalcium-Binding ProteinsCell CountCentral Nervous SystemCentral Nervous System DiseasesDisease Models, AnimalFacial Nerve DiseasesHumansMice, Inbred C57BLMice, TransgenicMicrofilament ProteinsNerve DegenerationParabiosisRadiation ChimeraStem Cells
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1,582
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26.84
field-weighted impact
References
47
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100%
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Citations per year
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References
Displacement of synaptic terminals from regenerating motoneurons by microglial cells
Cell and Tissue Research · 1968 · 865 citations
Microglial cell activation and proliferation precedes the onset of CNS autoimmunity
Journal of Neuroscience Research · 2005 · 408 citations
Microglia: a sensor for pathological events in the CNS
Trends in Neurosciences · 1996 · 4,373 citations
ATP mediates rapid microglial response to local brain injury in vivo
Nature Neuroscience · 2005 · 3,942 citations
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