review Open AccessTop 1% cited
The Microenvironmental Landscape of Brain Tumors
Cancer Cell · 2017 · Vol. 31(3) · pp. 326–341
Daniela F. Quail(McGill University)Johanna A. Joyce✉(Ludwig Cancer Research)
Glioma Diagnosis and TreatmentBrain Metastases and TreatmentFerroptosis and cancer prognosisTumor microenvironmentNeuroscienceBrain cancerRegulatorBlood–brain barrierImmune systemBiologyCancerComputational biologyMedicine
MeSH terms
Blood-Brain BarrierBrain NeoplasmsDendritic CellsHumansMacrophagesNeutrophilsT-LymphocytesWound HealingMicrogliaNeovascularization, PhysiologicTumor Microenvironment
Funding
- Breast Cancer Research Foundation
- Ludwig Institute for Cancer Research
- Université de Lausanne
- National Cancer Institute
Citations
1,790
FWCI
68.06
field-weighted impact
References
187
Percentile
100%
vs. same field & year
Citations per year
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References
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Vascular Normalization by Vascular Endothelial Growth Factor Receptor 2 Blockade Induces a Pressure Gradient Across the Vasculature and Improves Drug Penetration in Tumors
Cancer Research · 2004 · 1,179 citations
CSF-1R inhibition alters macrophage polarization and blocks glioma progression
Nature Medicine · 2013 · 2,418 citations
The blood-brain barrier in brain homeostasis and neurological diseases
Biochimica et Biophysica Acta (BBA) - Biomembranes · 2008 · 717 citations
Local self-renewal can sustain CNS microglia maintenance and function throughout adult life
Nature Neuroscience · 2007 · 1,582 citations
Astrocyte–endothelial interactions at the blood–brain barrier
Nature reviews. Neuroscience · 2005 · 5,452 citations
Microenvironmental regulation of tumor progression and metastasis
Nature Medicine · 2013 · 7,973 citations
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