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A gene-based association method for mapping traits using reference transcriptome data
Nature Genetics · 2015 · Vol. 47(9) · pp. 1091–1098
Eric R. Gamazon✉(Vanderbilt University)Heather E. Wheeler(University of Chicago)Kaanan P. Shah(University of Chicago)Sahar V. Mozaffari(University of Chicago)Keston Aquino-Michaels(University of Chicago)Robert J. Carroll(Vanderbilt University)Anne E. EylerJoshua C. Denny(Vanderbilt University)Dan L. Nicolae(University of Chicago)Nancy J. Cox(Vanderbilt University)Hae Kyung Im(University of Chicago)
Genetic Associations and EpidemiologyRNA modifications and cancerBioinformatics and Genomic NetworksBiologyGenome-wide association studyTranscriptomeGeneticsGenePhenotypeComputational biologyGenetic associationCandidate geneGene expression
MeSH terms
Chromosome MappingHumansPhenotypeGenetic Predisposition to DiseasePolymorphism, Single NucleotideGene Expression ProfilingGenome-Wide Association Study
Funding
- National Institutes of Health
Citations
2,069
FWCI
87.20
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58
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100%
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References
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The American Journal of Human Genetics · 2010 · 835 citations
Trait-Associated SNPs Are More Likely to Be eQTLs: Annotation to Enhance Discovery from GWAS
PLoS Genetics · 2010 · 1,408 citations
GCTA: A Tool for Genome-wide Complex Trait Analysis
The American Journal of Human Genetics · 2010 · 9,109 citations
GENCODE: The reference human genome annotation for The ENCODE Project
Genome Research · 2012 · 5,001 citations
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
Nature Genetics · 2010 · 2,560 citations
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