review Open AccessTop 1% cited
10 Years of GWAS Discovery: Biology, Function, and Translation
The American Journal of Human Genetics · 2017 · Vol. 101(1) · pp. 5–22
Peter M. Visscher✉(The University of Queensland)Naomi R. Wray(The University of Queensland)Qian Zhang(The University of Queensland)Pamela Sklar(Icahn School of Medicine at Mount Sinai)Mark I. McCarthy(Centre for Human Genetics)Matthew A. Brown(Translational Research Institute)Jian Yang(The University of Queensland)
Glycosylation and Glycoproteins ResearchGenomics and Phylogenetic StudiesMachine Learning in BioinformaticsGenome-wide association studyComputational biologyTranslation (biology)BiologyData scienceComputer scienceGeneticsSingle-nucleotide polymorphismGenotypeGene
MeSH terms
HumansGenetic Predisposition to DiseaseMultifactorial InheritanceGenome-Wide Association StudyTranslational Research, BiomedicalGenetic Pleiotropy
Funding
- Wellcome
- Sylvia and Charles Viertel Charitable Foundation
- Innovative Medicines Initiative
- National Institutes of Health
- Medical Research Council
- National Health and Medical Research Council
Citations
3,967
FWCI
174.85
field-weighted impact
References
150
Percentile
100%
vs. same field & year
Citations per year
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References
Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations
Nature Genetics · 2015 · 2,703 citations
Partitioning heritability by functional annotation using genome-wide association summary statistics
Nature Genetics · 2015 · 2,993 citations
Genome-wide efficient mixed-model analysis for association studies
Nature Genetics · 2012 · 3,909 citations
Finding the missing heritability of complex diseases
Nature · 2009 · 8,468 citations
A Versatile Gene-Based Test for Genome-wide Association Studies
The American Journal of Human Genetics · 2010 · 835 citations
The shared epitope hypothesis. an approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis
Arthritis & Rheumatism · 1987 · 2,570 citations
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs
Nature Genetics · 2013 · 2,335 citations
Heritability in the genomics era — concepts and misconceptions
Nature Reviews Genetics · 2008 · 1,936 citations
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