review Open AccessTop 1% cited
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
Nature Genetics · 2010 · Vol. 42(12) · pp. 1118–1125
André Franke✉(Kiel University)Dermot McGovern(Cedars-Sinai Medical Center)Jeffrey C. Barrett(Wellcome Sanger Institute)Kai Wang(Children's Hospital of Philadelphia)Graham Radford‐Smith(QIMR Berghofer Medical Research Institute)Tariq Ahmad(Peninsula College of Medicine and Dentistry)Charlie W. Lees(Western General Hospital)Tobias Balschun(Kiel University)James Lee(Addenbrooke's Hospital)Rebecca Roberts(University of Otago)Carl A. Anderson(Wellcome Sanger Institute)Joshua C. Bis(University of Washington)Suzanne Bumpstead(Wellcome Sanger Institute)David Ellinghaus(Kiel University)Eleonora A. Festen(University Medical Center Groningen)Michel Georges(University of Liège)Todd J. Green(Harvard University)Talin Haritunians(Cedars-Sinai Medical Center)Luke Jostins(Wellcome Sanger Institute)Anna Latiano(Casa Sollievo della Sofferenza)Christopher G. Mathew(King's College London)Grant W. Montgomery(QIMR Berghofer Medical Research Institute)Natalie J. Prescott(King's College London)Soumya Raychaudhuri(Harvard University)Jerome I. Rotter(Cedars-Sinai Medical Center)L. Philip Schumm(University of Chicago)Yashoda Sharma(Yale University)Lisa A. Simms(QIMR Berghofer Medical Research Institute)Kent D. Taylor(Cedars-Sinai Medical Center)David C. Whiteman(QIMR Berghofer Medical Research Institute)Cisca Wijmenga(University Medical Center Groningen)Robert N. Baldassano(Children's Hospital of Philadelphia)Murray L. Barclay(University of Otago)Theodore M. Bayless(Johns Hopkins Medicine)Stephan Brand(Ludwig-Maximilians-Universität München)Carsten Büning(Charité - Universitätsmedizin Berlin)Albert Cohen(Jewish General Hospital)J F. Colombel(Université de Lille)Mario Cottone(Ospedale Vincenzo Cervello)Laura Stronati(National Agency for New Technologies, Energy and Sustainable Economic Development)Ted Denson(Cincinnati Children's Hospital Medical Center)Martine De Vos(Ghent University Hospital)R. D’Incà(University of Padua)Marla C. Dubinsky(Cedars-Sinai Medical Center)Cathryn Edwards(Torbay Hospital)Tim Florin(Mater Health Services)Denis Franchimont(Erasmus Hospital)Richard B. Gearry(University of Otago)Jürgen Glas(Ludwig-Maximilians-Universität München)A. Van Gossum(Erasmus Hospital)Stephen L. Guthery(University of Utah)Jonas Halfvarson(Örebro University Hospital)Hein W. Verspaget(Leiden University Medical Center)Jean‐Pierre Hugot(Université Paris Cité)Amir Karban(Technion – Israel Institute of Technology)Debby Laukens(Ghent University Hospital)Ian C. Lawrance(University of Western Australia)Marc Lémann(Université Paris Cité)Arie Levine(Tel Aviv University)Cécile Libioulle(University of Liège)Édouard Louis(University of Liège)Craig Mowat(Ninewells Hospital)William G. Newman(University of Manchester)Julián Panés(Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas)Anne Phillips(Ninewells Hospital)Deborah D. Proctor(Yale University)Miguel Regueiro(University of Pittsburgh)Richard K. Russell(Stobhill Hospital)Paul RutgeertsJeremy Sanderson(St Thomas' Hospital)Miquel Sans(Consorci Institut D'Investigacions Biomediques August Pi I Sunyer)Frank Seibold(University Hospital of Bern)A. Hillary Steinhart(Mount Sinai Hospital)Pieter Stokkers(Academic Medical Center)Leif Törkvist(Karolinska Institutet)Gerd A. Kullak‐Ublick(University Hospital of Zurich)David C. Wilson(University of Edinburgh)Thomas D. Walters(SickKids Foundation)Stephan R. Targan(Cedars-Sinai Medical Center)Steven R. Brant(Johns Hopkins University)John D. Rioux(Université de Montréal)Mauro D’Amato(Karolinska Institutet)Rinse K. Weersma(University Medical Center Groningen)Subra Kugathasan(Emory University)Anne M. Griffiths(Hospital for Sick Children)John Mansfield(Newcastle University)Séverine VermeireRichard H. Duerr(University of Pittsburgh)Mark S. Silverberg(Mount Sinai Hospital)Jack Satsangi(University of Edinburgh)Stefan Schreiber(Kiel University)Judy H. Cho(Yale University)Vito Annese(Azienda Ospedaliero-Universitaria Careggi)Håkon Håkonarson(Children's Hospital of Philadelphia)Mark J. Daly(Center for Human Genetics)Miles Parkes(University of Cambridge)
Inflammatory Bowel DiseaseHelicobacter pylori-related gastroenterology studiesIL-33, ST2, and ILC PathwaysBiologyGenome-wide association studyGeneticsGenomeIn silicoGenetic associationDiseaseGeneCrohn's diseaseSingle-nucleotide polymorphism
MeSH terms
Crohn DiseaseHumansGenetic LinkageGenetic VariationReproducibility of ResultsGenome, HumanComputational BiologyGenetic Predisposition to DiseaseGenome-Wide Association StudyGenetic Loci
Funding
- Crohn's and Colitis Foundation of America
- Abbott Laboratories
- Wellcome Trust
- Crohn's and Colitis Foundation
- Cedars-Sinai Medical Center
- Action Medical Research
- National Institute for Health and Care Research
- King's College London
- Deutsche Forschungsgemeinschaft
- Fonds De La Recherche Scientifique - FNRS
- Fonds Wetenschappelijk Onderzoek
- Exzellenzclusters Entzündungsforschung
- National Institutes of Health
- Medical Research Council
- National Health and Medical Research Council
- National Heart, Lung, and Blood Institute
- National Institute of Diabetes and Digestive and Kidney Diseases
- National Center for Research Resources
Citations
2,560
FWCI
137.28
field-weighted impact
References
53
Percentile
100%
vs. same field & year
Citations per year
Cited by
Dysfunction of the intestinal microbiome in inflammatory bowel disease and treatment
Genome biology · 2012 · 2,736 citations
ACG Clinical Guideline: Management of Crohn's Disease in Adults
The American Journal of Gastroenterology · 2018 · 1,376 citations
MAGMA: Generalized Gene-Set Analysis of GWAS Data
PLoS Computational Biology · 2015 · 3,882 citations
Five Years of GWAS Discovery
The American Journal of Human Genetics · 2012 · 2,534 citations
JAK–STAT Signaling as a Target for Inflammatory and Autoimmune Diseases: Current and Future Prospects
Drugs · 2017 · 1,151 citations
Drug repurposing: progress, challenges and recommendations
Nature Reviews Drug Discovery · 2018 · 4,479 citations
Functional mapping and annotation of genetic associations with FUMA
Nature Communications · 2017 · 4,347 citations
A gene-based association method for mapping traits using reference transcriptome data
Nature Genetics · 2015 · 2,069 citations
References
A Unified Approach to Genotype Imputation and Haplotype-Phase Inference for Large Data Sets of Trios and Unrelated Individuals
The American Journal of Human Genetics · 2009 · 1,695 citations
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
Nature · 2007 · 9,601 citations
Rapid and Accurate Haplotype Phasing and Missing-Data Inference for Whole-Genome Association Studies By Use of Localized Haplotype Clustering
The American Journal of Human Genetics · 2007 · 3,489 citations
Janus kinases in immune cell signaling
Immunological Reviews · 2009 · 1,132 citations
Common SNPs explain a large proportion of the heritability for human height
Nature Genetics · 2010 · 4,788 citations
Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease
Nature Genetics · 2008 · 2,619 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.