article Open AccessTop 1% cited
Colocalization of GWAS and eQTL Signals Detects Target Genes
The American Journal of Human Genetics · 2016 · Vol. 99(6) · pp. 1245–1260
Farhad Hormozdiari(University of California, Los Angeles)Martijn van de Bunt(Centre for Human Genetics)Ayellet V. Segrè(Broad Institute)Xiao Li(Broad Institute)Jong Wha J. Joo(University of California, Los Angeles)Michael Bilow(University of California, Los Angeles)Jae Hoon Sul(University of California, Los Angeles)Sriram Sankararaman(University of California, Los Angeles)Bogdan Paşaniuc(University of California, Los Angeles)Eleazar Eskin✉(University of California, Los Angeles)
Genetic Associations and EpidemiologyBioinformatics and Genomic NetworksGenomics and Chromatin DynamicsExpression quantitative trait lociGenome-wide association studyLocus (genetics)Linkage disequilibriumComputational biologyQuantitative trait locusBiologyGenetic associationGeneticsImputation (statistics)
MeSH terms
Gene Expression RegulationGenotypeGlucoseHumansInsulinModels, GeneticOrgan SpecificityProbabilityModels, StatisticalLinkage DisequilibriumSample SizeGenetic Predisposition to DiseaseQuantitative Trait LociGenome-Wide Association StudyDatasets as Topic
Funding
- National Science Foundation
- Broad Institute
- University of Oxford
- Novo Nordisk
- National Institutes of Health
- National Institute of Neurological Disorders and Stroke
Citations
762
FWCI
47.13
field-weighted impact
References
50
Percentile
100%
vs. same field & year
Citations per year
References
Linkage Disequilibrium in Humans: Models and Data
The American Journal of Human Genetics · 2001 · 1,311 citations
Trait-Associated SNPs Are More Likely to Be eQTLs: Annotation to Enhance Discovery from GWAS
PLoS Genetics · 2010 · 1,408 citations
Bayesian Test for Colocalisation between Pairs of Genetic Association Studies Using Summary Statistics
PLoS Genetics · 2014 · 4,336 citations
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
Nature · 2007 · 9,601 citations
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
Nature Genetics · 2010 · 2,224 citations
Five Years of GWAS Discovery
The American Journal of Human Genetics · 2012 · 2,534 citations
A gene-based association method for mapping traits using reference transcriptome data
Nature Genetics · 2015 · 2,069 citations
Integrative approaches for large-scale transcriptome-wide association studies
Nature Genetics · 2016 · 2,654 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.