article Open AccessTop 1% cited
Differential analysis of gene regulation at transcript resolution with RNA-seq
Nature Biotechnology · 2012 · Vol. 31(1) · pp. 46–53
Cole Trapnell(Harvard University)David G. Hendrickson(Harvard University)Martin Sauvageau(Harvard University)Loyal A. Goff(Massachusetts Institute of Technology)John L. Rinn(Broad Institute)Lior Pachter✉(University of California, Berkeley)
Cancer-related molecular mechanisms researchRNA Research and SplicingRNA modifications and cancerBiologyRNA-SeqAlternative splicingGeneGene expressionRNATranscription (linguistics)GeneticsRNA splicingTranscriptome
MeSH terms
Homeobox A1 ProteinFibroblastsGene Expression RegulationHeLa CellsHumansLungRNA, MessengerTranscription FactorsSequence Analysis, RNAHomeodomain Proteins
Funding
- Damon Runyon Cancer Research Foundation
- National Institutes of Health
Citations
3,712
FWCI
69.71
field-weighted impact
References
50
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100%
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References
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Nature Genetics · 2008 · 3,972 citations
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DEGseq: an R package for identifying differentially expressed genes from RNA-seq data
Bioinformatics · 2009 · 4,836 citations
Detecting differential usage of exons from RNA-seq data
Genome Research · 2012 · 1,626 citations
RNA-seq: An assessment of technical reproducibility and comparison with gene expression arrays
Genome Research · 2008 · 2,821 citations
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Proceedings of the National Academy of Sciences · 2005 · 55,472 citations
Improving RNA-Seq expression estimates by correcting for fragment bias
Genome biology · 2011 · 1,812 citations
Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation
Nature Biotechnology · 2010 · 16,341 citations
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