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Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation

Nature Biotechnology · 2010 · Vol. 28(5) · pp. 511–515
Cole TrapnellBrian A. WilliamsGeo PerteaA MortazaviGordon KwanMarijke J. van BarenSteven L. SalzbergB WoldLior Pachter
RNA Research and SplicingRNA modifications and cancerCancer-related molecular mechanisms researchBiologyRNA-SeqGeneRNA splicingTranscriptomeComputational biologyAlternative splicingGeneticsGenomeDe novo transcriptome assembly

MeSH terms

AlgorithmsAnimalsCell DifferentiationCell LineRNA, MessengerSoftwareProto-Oncogene Proteins c-mycGenomeSequence Analysis, RNAProtein IsoformsOligonucleotide Array Sequence AnalysisGene Expression ProfilingMice
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Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation · Scinovex