review Open AccessTop 1% cited
p21 in cancer: intricate networks and multiple activities
Nature reviews. Cancer · 2009 · Vol. 9(6) · pp. 400–414
Tarek Abbas✉(University of Virginia)Anindya Dutta(University of Virginia)
Cancer-related Molecular PathwaysEpigenetics and DNA MethylationKruppel-like factors researchEffectorSuppressorFunction (biology)Cell cycleCancerCell biologyCancer researchKinaseBiologyCell cycle checkpoint
MeSH terms
AnimalsCell CycleHumansNeoplasmsTumor Suppressor Protein p53Cyclin-Dependent Kinase Inhibitor p21
Funding
- National Institutes of Health
Citations
2,716
FWCI
47.84
field-weighted impact
References
236
Percentile
100%
vs. same field & year
Citations per year
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References
Cytoplasmic localization of p21Cip1/WAF1 by Akt-induced phosphorylation in HER-2/neu-overexpressing cells
Nature Cell Biology · 2001 · 1,150 citations
Regulation of the G2/M transition by p53
Oncogene · 2001 · 1,554 citations
DNA damage checkpoints: from initiation to recovery or adaptation
Current Opinion in Cell Biology · 2007 · 771 citations
Oncogenic functions of tumour suppressor p21Waf1/Cip1/Sdi1: association with cell senescence and tumour-promoting activities of stromal fibroblasts
Cancer Letters · 2002 · 445 citations
WAF1, a potential mediator of p53 tumor suppression
Cell · 1993 · 8,369 citations
CDK Inhibitors: Cell Cycle Regulators and Beyond
Developmental Cell · 2008 · 1,146 citations
Cell cycle, CDKs and cancer: a changing paradigm
Nature reviews. Cancer · 2009 · 3,885 citations
Transcriptional Regulation of the p21(WAF1/CIP1)Gene
Experimental Cell Research · 1999 · 664 citations
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