reviewTop 10% cited
Oncogenic functions of tumour suppressor p21Waf1/Cip1/Sdi1: association with cell senescence and tumour-promoting activities of stromal fibroblasts
Cancer Letters · 2002 · Vol. 179(1) · pp. 1–14
Igor B. Roninson✉(University of Illinois Chicago)
Cancer-related Molecular PathwaysCancer Research and TreatmentsUbiquitin and proteasome pathwaysBiologyCancer researchParacrine signallingCell biologyCarcinogenesisSenescenceStromal cellCell cycleCyclinTranscription factor
MeSH terms
AnimalsCell CycleCell LineCell Transformation, NeoplasticDNA RepairFibroblastsGene Expression RegulationHumansMitosisNeoplasmsCyclinsCellular SenescenceApoptosisMice, KnockoutCyclin-Dependent Kinase Inhibitor p21
Citations
445
FWCI
9.96
field-weighted impact
References
154
Percentile
99%
vs. same field & year
Citations per year
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References
Inhibition of cyclin-dependent kinases by p21.
Molecular Biology of the Cell · 1995 · 1,018 citations
Cloning of Senescent Cell-Derived Inhibitors of DNA Synthesis Using an Expression Screen
Experimental Cell Research · 1994 · 1,347 citations
WAF1, a potential mediator of p53 tumor suppression
Cell · 1993 · 8,369 citations
Heterotypic Signaling between Epithelial Tumor Cells and Fibroblasts in Carcinoma Formation
Experimental Cell Research · 2001 · 550 citations
Transcriptional Regulation of the p21(WAF1/CIP1)Gene
Experimental Cell Research · 1999 · 664 citations
Oncogenic ras Provokes Premature Cell Senescence Associated with Accumulation of p53 and p16INK4a
Cell · 1997 · 5,018 citations
The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases
Cell · 1993 · 5,653 citations
The biology of replicative senescence
European Journal of Cancer · 1997 · 531 citations
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