articleTop 1% cited

WAF1, a potential mediator of p53 tumor suppression

Cell · 1993 · Vol. 75(4) · pp. 817–825

Wafik S. El‐Deiry✉(Johns Hopkins University)Takashi Tokino(Johns Hopkins Medicine)Victor E. Velculescu(Johns Hopkins Medicine)Daniel B. Levy(Johns Hopkins Medicine)Ramon Parsons(Johns Hopkins University)J.M. Trent(National Human Genome Research Institute)David Pei‐Cheng Lin(Thomas Jefferson University)W E Mercer(Thomas Jefferson University)K W Kinzler(Johns Hopkins Medicine)Bert Vogelstein(Johns Hopkins University)

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Cancer-related Molecular Pathways Epigenetics and DNA Methylation RNA modifications and cancerBiologyEnhancerGeneTumor suppressor geneSuppression subtractive hybridizationMolecular biologyReporter geneMutantComplementary DNAGene expression

MeSH terms

Amino Acid SequenceAnimalsBase SequenceCell CycleChromosomes, Human, Pair 6Cloning, MolecularGene Expression RegulationGenesHumansMolecular Sequence DataNuclear ProteinsNucleic Acid HybridizationPromoter Regions, GeneticRNA, MessengerGenes, Tumor Suppressor

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The Multifaceted p21 (Cip1/Waf1/CDKN1A) in Cell Differentiation, Migration and Cancer Therapy