review Open AccessTop 1% cited
Cell cycle arrest through indirect transcriptional repression by p53: I have a DREAM
Cell Death and Differentiation · 2017 · Vol. 25(1) · pp. 114–132
Kurt Engeland✉(Leipzig University)
Cancer-related Molecular PathwaysMicrotubule and mitosis dynamicsUbiquitin and proteasome pathwaysE2FBiologyCell cycleCell biologyRetinoblastoma proteinRepressorCancer researchCell cycle checkpointCytokinesisTumor suppressor gene
MeSH terms
AnimalsDNAGene Expression RegulationHumansNeoplasmsRepressor ProteinsDown-RegulationTumor Suppressor Protein p53Genes, cdcCytokinesisE2F Transcription FactorsCell Cycle CheckpointsG1 Phase Cell Cycle Checkpoints
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References
Regulation of the G2/M transition by p53
Oncogene · 2001 · 1,554 citations
Inhibition of cyclin-dependent kinases by p21.
Molecular Biology of the Cell · 1995 · 1,018 citations
WAF1, a potential mediator of p53 tumor suppression
Cell · 1993 · 8,369 citations
The spindle-assembly checkpoint in space and time
Nature Reviews Molecular Cell Biology · 2007 · 2,199 citations
The p21Cip1 and p27Kip1 CDK `inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts
The EMBO Journal · 1999 · 1,141 citations
CDK inhibitors: positive and negative regulators of G1-phase progression
Genes & Development · 1999 · 6,077 citations
Gene expression profiling predicts clinical outcome of breast cancer
Nature · 2002 · 9,574 citations
p21 in cancer: intricate networks and multiple activities
Nature reviews. Cancer · 2009 · 2,716 citations
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