review Open AccessTop 1% cited

CDK Inhibitors: Cell Cycle Regulators and Beyond

Developmental Cell · 2008 · Vol. 14(2) · pp. 159–169

Arnaud Besson✉(Centre National de la Recherche Scientifique)Steven F. Dowdy(University of California San Diego)James M. Roberts(Cape Town HVTN Immunology Laboratory / Hutchinson Centre Research Institute of South Africa)

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Cancer-related Molecular Pathways Microtubule and mitosis dynamics Cancer, Hypoxia, and MetabolismBiologyCyclin-dependent kinaseCell biologyCell cycleComputational biologyCellGenetics

MeSH terms

AnimalsCell CycleCytoskeletonGene Expression RegulationHumansApoptosisTumor Suppressor ProteinsCyclin-Dependent Kinase Inhibitor Proteins

Citations

1,146

FWCI

33.66

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References

151

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References

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Rho GTPases Control Polarity, Protrusion, and Adhesion during Cell Movement

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p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest.

Genes & Development · 1994 · 1,972 citations

Oncogenic functions of tumour suppressor p21Waf1/Cip1/Sdi1: association with cell senescence and tumour-promoting activities of stromal fibroblasts

Cancer Letters · 2002 · 445 citations

WAF1, a potential mediator of p53 tumor suppression

Cell · 1993 · 8,369 citations

Transcriptional Regulation of the p21(WAF1/CIP1)Gene

Experimental Cell Research · 1999 · 664 citations

Differing modes of tumour cell invasion have distinct requirements for Rho/ROCK signalling and extracellular proteolysis

Nature Cell Biology · 2003 · 1,132 citations

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