article Open AccessTop 10% cited
Pharmacological Characterization of 4-hydroxy-N-desmethyl Tamoxifen, a Novel Active Metabolite of Tamoxifen
Breast Cancer Research and Treatment · 2004 · Vol. 85(2) · pp. 151–159
Michael D. Johnson✉(Georgetown University)Hong Zuo(Georgetown University)Kyung-Hoon Lee(Indiana University School of Medicine)Joseph P. Trebley(Purdue University West Lafayette)James M. Rae(University of Michigan–Ann Arbor)Ross Weatherman(Indiana University School of Medicine)Zeruesanay Desta(Indiana University – Purdue University Indianapolis)David A. Flockhart(Indiana University – Purdue University Indianapolis)Todd C. Skaar(Indiana University – Purdue University Indianapolis)
Estrogen and related hormone effectsCancer Treatment and PharmacologyEndometriosis Research and TreatmentTamoxifenDesmethylActive metaboliteMetaboliteBreast cancerPharmacologyInternal medicineMedicineBiologyEndocrinology
MeSH terms
Breast NeoplasmsCell DivisionDrug InteractionsFemaleGenotypeHumansReceptors, EstrogenTamoxifenTumor Cells, CulturedCytochrome P-450 CYP2D6
Funding
- American Cancer Society
- Purdue University
- National Cancer Institute
Citations
455
FWCI
7.58
field-weighted impact
References
22
Percentile
98%
vs. same field & year
Citations per year
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References
A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding
Analytical Biochemistry · 1976 · 225,297 citations
Tamoxifen for Prevention of Breast Cancer: Report of the National Surgical Adjuvant Breast and Bowel Project P-1 Study
JNCI Journal of the National Cancer Institute · 1998 · 5,500 citations
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
Analytical Biochemistry · 1976 · 209,807 citations
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