reviewTop 1% cited
How regulatory T cells work
Nature reviews. Immunology · 2008 · Vol. 8(7) · pp. 523–532
Dario A.A. Vignali✉(St. Jude Children's Research Hospital)Lauren W. Collison(St. Jude Children's Research Hospital)Creg J. Workman(St. Jude Children's Research Hospital)
T-cell and B-cell ImmunologyImmune Cell Function and InteractionCancer Immunotherapy and BiomarkersEffectorImmune systemImmunologyRegulatory T cellLimitingImmunityFunction (biology)Peripheral toleranceBiologyTreg cell
MeSH terms
AnimalsCytotoxicity, ImmunologicDendritic CellsHumansT-Lymphocyte SubsetsCytokinesT-Lymphocytes, RegulatoryForkhead Transcription FactorsGranzymesPerforin
Funding
- American Lebanese Syrian Associated Charities
Citations
3,325
FWCI
62.16
field-weighted impact
References
131
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100%
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References
The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3
Nature Genetics · 2001 · 3,333 citations
Signaling by intrathymic cytokines, not T cell antigen receptors, specifies CD8 lineage choice and promotes the differentiation of cytotoxic-lineage T cells
Nature Immunology · 2010 · 5,839 citations
Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse
Nature Genetics · 2001 · 2,563 citations
Ido expression by dendritic cells: tolerance and tryptophan catabolism
Nature reviews. Immunology · 2004 · 2,302 citations
Interleukin‐10‐secreting type 1 regulatory T cells in rodents and humans
Immunological Reviews · 2006 · 1,152 citations
Transient expression of FOXP3 in human activated nonregulatory CD4 <sup>+</sup> T cells
European Journal of Immunology · 2006 · 988 citations
CD4+CD25+ Immunoregulatory T Cells
Immunity · 2002 · 1,397 citations
Interleukin‐2 is essential for CD4<sup>+</sup>CD25<sup>+</sup> regulatory T cell function
European Journal of Immunology · 2004 · 530 citations
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