reviewTop 1% cited
Ido expression by dendritic cells: tolerance and tryptophan catabolism
Nature reviews. Immunology · 2004 · Vol. 4(10) · pp. 762–774
Andrew L. Mellor✉(Augusta University)David H. Munn(Augusta University)
Tryptophan and brain disordersImmune Cell Function and InteractionReproductive System and PregnancyImmune toleranceIndoleamine 2,3-dioxygenaseCatabolismImmunologyBiologyTryptophan MetabolismTryptophanCell biologyImmune systemAmino acid
MeSH terms
AnimalsDendritic CellsHumansImmune ToleranceImmunosuppression TherapyTryptophanTryptophan OxygenaseModels, ImmunologicalIndoleamine-Pyrrole 2,3,-Dioxygenase
Funding
- National Institutes of Health
Citations
2,302
FWCI
47.69
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References
154
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100%
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References
Relationship between interferon‐γ, indoleamine 2,3‐dioxygenase, and tryptophan catabolism
The FASEB Journal · 1991 · 1,066 citations
Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase
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Regulatory T cells mediate maternal tolerance to the fetus
Nature Immunology · 2004 · 1,627 citations
An essential role for Scurfin in CD4+CD25+ T regulatory cells
Nature Immunology · 2003 · 2,816 citations
Inhibition of T Cell Proliferation by Macrophage Tryptophan Catabolism
The Journal of Experimental Medicine · 1999 · 1,603 citations
Human bone marrow stromal cells inhibit allogeneic T-cell responses by indoleamine 2,3-dioxygenase–mediated tryptophan degradation
Blood · 2004 · 1,627 citations
Cancer immunoediting: from immunosurveillance to tumor escape
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