review Open AccessTop 1% cited
Regulatory T Cells and Immune Tolerance
Cell · 2008 · Vol. 133(5) · pp. 775–787
Shimon Sakaguchi✉(Kyoto University)Tomoyuki Yamaguchi(Kyoto University)Takashi Nomura(Kyoto University)Masahiro Ono(Kyoto University)
T-cell and B-cell ImmunologyImmune Cell Function and InteractionImmunotherapy and Immune ResponsesBiologyImmune systemImmunologyImmune toleranceAntigenFunction (biology)Cell biologySelf ToleranceDiseaseT cell
MeSH terms
AnimalsAutoimmune DiseasesHumansThymus GlandSelf ToleranceT-Lymphocytes, Regulatory
Funding
- Wellcome Trust
- Santen
Citations
5,180
FWCI
96.66
field-weighted impact
References
115
Percentile
100%
vs. same field & year
Citations per year
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References
Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide
Nature Immunology · 2001 · 1,632 citations
Signaling by intrathymic cytokines, not T cell antigen receptors, specifies CD8 lineage choice and promotes the differentiation of cytotoxic-lineage T cells
Nature Immunology · 2010 · 5,839 citations
Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse
Nature Genetics · 2001 · 2,563 citations
Epigenetic Control of the foxp3 Locus in Regulatory T Cells
PLoS Biology · 2007 · 1,227 citations
CD4+CD25+ Immunoregulatory T Cells
Immunity · 2002 · 1,397 citations
Control of Regulatory T Cell Development by the Transcription Factor <i>Foxp3</i>
Science · 2003 · 8,062 citations
Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self
Nature Immunology · 2005 · 2,654 citations
An essential role for Scurfin in CD4+CD25+ T regulatory cells
Nature Immunology · 2003 · 2,816 citations
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