articleTop 1% cited
Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide
Nature Immunology · 2001 · Vol. 2(4) · pp. 301–306
Martha S. Jordan✉(The Wistar Institute)Alina C. Boesteanu(The Wistar Institute)Amy J. Reed(The Wistar Institute)Andria L. Petrone(The Wistar Institute)Andrea E. Holenbeck(The Wistar Institute)Melissa A. Lerman(The Wistar Institute)Ali Naji(University of Pennsylvania)Andrew J. Caton(The Wistar Institute)
T-cell and B-cell ImmunologyImmune Cell Function and InteractionImmunotherapy and Immune ResponsesT-cell receptorNegative selectionIL-2 receptorThymocyteBiologyCell biologyAgonistReceptorRegulatory T cellAutoimmunity
MeSH terms
Amino Acid SequenceAnimalsAutoantigensMice, Inbred BALB CMice, TransgenicPhenotypeReceptors, Antigen, T-CellThymus GlandReceptors, Interleukin-2CD4-Positive T-LymphocytesSelf ToleranceMice
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References
CD4+CD25+ Immunoregulatory T Cells Suppress Polyclonal T Cell Activation In Vitro by Inhibiting Interleukin 2 Production
The Journal of Experimental Medicine · 1998 · 2,598 citations
Thymus and Autoimmunity: Production of CD25+CD4+ Naturally Anergic and Suppressive T Cells as a Key Function of the Thymus in Maintaining Immunologic Self-Tolerance
The Journal of Immunology · 1999 · 1,196 citations
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