Scinovex
article

Sulfasalazine, a potent suppressor of lymphoma growth by inhibition of the xc − cystine transporter: a new action for an old drug

Leukemia · 2001 · Vol. 15(10) · pp. 1633–1640
PW GoutAR BuckleyCR SimmsNicholas Bruchovsky
Amino Acid Enzymes and MetabolismDrug Transport and Resistance MechanismsBiomedical Research and PathophysiologySulfasalazineCystineGrowth inhibitionLymphomaPharmacologyChemistryCancer researchBiologyMedicineBiochemistry

MeSH terms

AnimalsAnti-Inflammatory Agents, Non-SteroidalAntineoplastic AgentsCarrier ProteinsCell DivisionDrug Evaluation, PreclinicalHumansInjections, IntraperitonealLymphomaNeoplasm TransplantationRats, Inbred StrainsSulfasalazineTumor Cells, CulturedInhibitory Concentration 50Amino Acid Transport System y+

Funding

  • Ohio Cancer Research Associates
  • BC Cancer Agency
Citations
629
FWCI
0.76
field-weighted impact
References
42
Percentile
72%
vs. same field & year
Citations per year
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