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Goal-directed coagulation management of major trauma patients using thromboelastometry (ROTEM®)-guided administration of fibrinogen concentrate and prothrombin complex concentrate
Critical Care · 2010 · Vol. 14(2) · pp. R55–R55
Herbert Schöchl(Unfallkrankenhaus Salzburg)Ulrike Nienaber(Witten/Herdecke University)Georg HoferWolfgang VoelckelCsilla Jámbor(München Klinik)Gisela Scharbert(Medical University of Vienna)Sibylle A. Kozek‐Langenecker(Medical University of Vienna)Cristina Solomon✉(Salzburger Landeskliniken)
Abstract
ROTEM-guided haemostatic therapy, with fibrinogen concentrate as first-line haemostatic therapy and additional PCC, was goal-directed and fast. A favourable survival rate was observed. Prospective, randomized trials to investigate this therapeutic alternative further appear warranted.
Trauma, Hemostasis, Coagulopathy, ResuscitationTrauma and Emergency Care StudiesHemostasis and retained surgical itemsThromboelastometryMedicineProthrombin complex concentrateFibrinogenCoagulopathyCoagulation testingAnesthesiaInjury Severity ScoreProthrombin timeFibrin
MeSH terms
AdultBlood Coagulation FactorsFemaleFibrinogenHemorrhageHemostatic TechniquesHumansMaleMiddle AgedProthrombinRetrospective StudiesThrombelastographyWounds and Injuries
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The Ratio of Blood Products Transfused Affects Mortality in Patients Receiving Massive Transfusions at a Combat Support Hospital
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