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Molecular Signature of CD8+ T Cell Exhaustion during Chronic Viral Infection
Immunity · 2007 · Vol. 27(4) · pp. 670–684
E. John Wherry✉(Emory University)Sang‐Jun HaSusan M. KaechW. Nicholas Haining(Dana-Farber Cancer Institute)Surojit SarkarVrinda KaliaShruti SubramaniamJoseph N. BlattmanDaniel L. BarberRafi Ahmed
Cancer Immunotherapy and BiomarkersT-cell and B-cell ImmunologyDiabetes and associated disordersLymphocytic choriomeningitisBiologyCD8Chronic infectionImmunologyCytotoxic T cellT cellImmune systemGenetics
MeSH terms
AnimalsCell DifferentiationChronic DiseaseFemaleFlow CytometryImmunologic MemoryLymphocyte ActivationLymphocytic choriomeningitis virusMice, Inbred C57BLMolecular Sequence DataPhenotypeVirus DiseasesGene ExpressionClonal AnergyCD8-Positive T-Lymphocytes
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