article Open AccessTop 1% cited
Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection
Nature Immunology · 2008 · Vol. 10(1) · pp. 29–37
Shawn D. Blackburn✉Haina Shin(The Wistar Institute)W. Nicholas Haining(Harvard University)Tao Zou(The Wistar Institute)Creg J. Workman(St. Jude Children's Research Hospital)Antonio Polley(The Wistar Institute)Michael R. Betts(University of Pennsylvania)Gordon J. Freeman(Dana-Farber Cancer Institute)Dario A.A. Vignali(St. Jude Children's Research Hospital)E. John Wherry(The Wistar Institute)
Immune Cell Function and InteractionT-cell and B-cell ImmunologyCAR-T cell therapy researchReceptorBiologyCD8Inhibitory postsynaptic potentialT cellCytotoxic T cellImmunologyCellImmune systemCell biology
MeSH terms
Lymphocyte Activation Gene 3 ProteinAnimalsAntigens, SurfaceChronic DiseaseDisease Models, AnimalImmunologic MemoryLymphocyte ActivationLymphocytic ChoriomeningitisLymphocytic choriomeningitis virusMice, Inbred C57BLReceptors, ImmunologicDown-RegulationAntigens, CDCD8-Positive T-LymphocytesApoptosis Regulatory Proteins
Citations
2,037
FWCI
25.48
field-weighted impact
References
58
Percentile
100%
vs. same field & year
Citations per year
Cited by
Immune checkpoints and their inhibition in cancer and infectious diseases
European Journal of Immunology · 2017 · 533 citations
<scp>LAG</scp>3 (<scp>CD</scp>223) as a cancer immunotherapy target
Immunological Reviews · 2017 · 946 citations
Follicular Helper CD4 T Cells (T<sub>FH</sub>)
Annual Review of Immunology · 2011 · 2,672 citations
PD‐1/PD‐L1 immune checkpoint: Potential target for cancer therapy
Journal of Cellular Physiology · 2018 · 506 citations
CD8 T Cell Exhaustion During Chronic Viral Infection and Cancer
Annual Review of Immunology · 2019 · 1,900 citations
Immune Inhibitory Molecules LAG-3 and PD-1 Synergistically Regulate T-cell Function to Promote Tumoral Immune Escape
Cancer Research · 2011 · 1,624 citations
T-cell exhaustion in chronic hepatitis B infection: current knowledge and clinical significance
Cell Death and Disease · 2015 · 377 citations
T Cell Dysfunction in Cancer
Cancer Cell · 2018 · 1,287 citations
References
Programmed Death-1 Ligand 1 Interacts Specifically with the B7-1 Costimulatory Molecule to Inhibit T Cell Responses
Immunity · 2007 · 1,731 citations
Lineage relationship and protective immunity of memory CD8 T cell subsets
Nature Immunology · 2003 · 1,836 citations
Molecular Signature of CD8+ T Cell Exhaustion during Chronic Viral Infection
Immunity · 2007 · 2,096 citations
The function of programmed cell death 1 and its ligands in regulating autoimmunity and infection
Nature Immunology · 2007 · 1,501 citations
Molecular Classification of Cancer: Class Discovery and Class Prediction by Gene Expression Monitoring
Science · 1999 · 11,587 citations
Memory CD8 T-Cell Differentiation during Viral Infection
Journal of Virology · 2004 · 858 citations
Viral Immune Evasion Due to Persistence of Activated T Cells Without Effector Function
The Journal of Experimental Medicine · 1998 · 1,950 citations
Characterization of Hepatitis B Virus (HBV)-Specific T-Cell Dysfunction in Chronic HBV Infection
Journal of Virology · 2007 · 893 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.