article Open AccessTop 1% cited
Adipocyte Death, Adipose Tissue Remodeling, and Obesity Complications
Diabetes · 2007 · Vol. 56(12) · pp. 2910–2918
Katherine J. Strissel✉(Jean Mayer Human Nutrition Research Center on Aging)Zlatina S. Stancheva(Tufts University)Hideaki Miyoshi(Jean Mayer Human Nutrition Research Center on Aging)James W. Perfield(Jean Mayer Human Nutrition Research Center on Aging)Jason DeFuria(Jean Mayer Human Nutrition Research Center on Aging)Zoe Jick(Jean Mayer Human Nutrition Research Center on Aging)Andrew S. Greenberg(Jean Mayer Human Nutrition Research Center on Aging)Martin S. Obin(Tufts University)
Abstract
These results implicate depot-selective adipocyte death and M Phi-mediated AT remodeling in inflammatory and metabolic complications of murine obesity.
Adipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and MetabolismCardiovascular Disease and AdiposityAdipocyteInternal medicineEndocrinologyAdipose tissueInsulin resistanceMedicineBiologyInsulin
MeSH terms
Adipose TissueAnimalsDisease Models, AnimalInflammationMacrophagesMaleMice, Inbred BALB CObesityCell DeathAdipocytesMice
Funding
- U.S. Public Health Service
- Agricultural Research Service
Citations
973
FWCI
24.69
field-weighted impact
References
55
Percentile
100%
vs. same field & year
Citations per year
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References
Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes
Genome biology · 2002 · 19,887 citations
Human adipose tissue macrophages are of an anti-inflammatory phenotype but capable of excessive pro-inflammatory mediator production
International Journal of Obesity · 2007 · 539 citations
Review article: Is obesity an inflammatory illness? Role of low‐grade inflammation and macrophage infiltration in human white adipose tissue
BJOG An International Journal of Obstetrics & Gynaecology · 2006 · 410 citations
Obesity is associated with macrophage accumulation in adipose tissue
Journal of Clinical Investigation · 2003 · 8,580 citations
Monocyte and macrophage heterogeneity
Nature reviews. Immunology · 2005 · 5,112 citations
Reduction of Macrophage Infiltration and Chemoattractant Gene Expression Changes in White Adipose Tissue of Morbidly Obese Subjects After Surgery-Induced Weight Loss
Diabetes · 2005 · 1,145 citations
Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
Journal of Clinical Investigation · 2003 · 5,825 citations
Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans
Journal of Lipid Research · 2005 · 2,454 citations
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