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Adipocyte Death, Adipose Tissue Remodeling, and Obesity Complications

Diabetes · 2007 · Vol. 56(12) · pp. 2910–2918
Katherine J. StrisselZlatina S. StanchevaHideaki MiyoshiJames W. PerfieldJason DeFuriaZoe JickAndrew S. GreenbergMartin S. Obin

Abstract

These results implicate depot-selective adipocyte death and M Phi-mediated AT remodeling in inflammatory and metabolic complications of murine obesity.

Adipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and MetabolismCardiovascular Disease and AdiposityAdipocyteInternal medicineEndocrinologyAdipose tissueInsulin resistanceMedicineBiologyInsulin

MeSH terms

Adipose TissueAnimalsDisease Models, AnimalInflammationMacrophagesMaleMice, Inbred BALB CObesityCell DeathAdipocytesMice

Funding

  • U.S. Public Health Service
  • Agricultural Research Service
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