articleTop 1% cited
Human adipose tissue macrophages are of an anti-inflammatory phenotype but capable of excessive pro-inflammatory mediator production
International Journal of Obesity · 2007 · Vol. 31(9) · pp. 1420–1428
Maximilian Zeyda✉(Medical University of Vienna)David Farmer(Medical University of Vienna)Jelena Todoric(Medical University of Vienna)Oskar C. Aszmann(Medical University of Vienna)Maria Speiser(Medical University of Vienna)Georg Györi(Medical University of Vienna)Gerhard J. Zlabinger(Medical University of Vienna)Thomas M. Stulnig(Medical University of Vienna)
Adipokines, Inflammation, and Metabolic DiseasesImmune cells in cancerAdipose Tissue and MetabolismAdipose tissue macrophagesAdipose tissueInflammationCD163CD14MacrophageMannose receptorScavenger receptorMonocyteTumor necrosis factor alpha
MeSH terms
Adipose TissueDiabetes Mellitus, Type 2FemaleHumansInsulin ResistanceMacrophagesMaleObesityPhenotypeInterleukin-10Inflammation MediatorsInterleukin 1 Receptor Antagonist Protein
Funding
- Austrian Science Fund
Citations
539
FWCI
19.79
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References
44
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100%
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References
Obesity-induced inflammatory changes in adipose tissue
Journal of Clinical Investigation · 2003 · 1,765 citations
Obesity is associated with macrophage accumulation in adipose tissue
Journal of Clinical Investigation · 2003 · 8,580 citations
Alternative activation of macrophages
Nature reviews. Immunology · 2003 · 6,118 citations
Obesity and insulin resistance
Journal of Clinical Investigation · 2000 · 3,203 citations
Macrophages in human visceral adipose tissue: increased accumulation in obesity and a source of resistin and visfatin
Diabetologia · 2006 · 686 citations
Interleukin-1β-Induced Insulin Resistance in Adipocytes through Down-Regulation of Insulin Receptor Substrate-1 Expression
Endocrinology · 2006 · 672 citations
Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
Journal of Clinical Investigation · 2003 · 5,825 citations
Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans
Journal of Lipid Research · 2005 · 2,454 citations
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