reviewTop 1% cited
Mechanisms of caspase activation
Current Opinion in Cell Biology · 2003 · Vol. 15(6) · pp. 725–731
Kelly M. Boatright(Sanford Burnham Prebys Medical Discovery Institute)Guy S. Salvesen✉(University of California, San Diego)
Cell death mechanisms and regulationAutophagy in Disease and TherapyNF-κB Signaling PathwaysZymogenCaspaseBiologyCell biologyCleavage (geology)ApoptosisCaspase 2Mechanism (biology)ProteaseNLRP1
MeSH terms
AnimalsCytosolEnzyme ActivationHumansModels, BiologicalApoptosisDimerizationCaspasesCaspase 3Caspase 7Caspase 8Caspase 10
Citations
1,369
FWCI
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References
An APAF-1·Cytochrome c Multimeric Complex Is a Functional Apoptosome That Activates Procaspase-9
Journal of Biological Chemistry · 1999 · 2,079 citations
The Inflammasome
Molecular Cell · 2002 · 5,936 citations
Mechanisms of Caspase Activation and Inhibition during Apoptosis
Molecular Cell · 2002 · 1,810 citations
Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade
Cell · 1997 · 7,227 citations
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