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Interleukin-1 and IL-23 Induce Innate IL-17 Production from γδ T Cells, Amplifying Th17 Responses and Autoimmunity

Immunity · 2009 · Vol. 31(2) · pp. 331–341
Caroline E. SuttonStephen J. LalorCheryl SweeneyCorinna F. BreretonEd C. LavelleKingston H. G. Mills
Psoriasis: Treatment and PathogenesisDermatology and Skin DiseasesImmunodeficiency and Autoimmune DisordersBiologyInterleukin 23AutoimmunityInterleukin 17ImmunologyInterleukin 15InterleukinCell biologyInflammationCytokine

MeSH terms

Interleukin-22Interleukin-21AnimalsDendritic CellsEncephalomyelitis, Autoimmune, ExperimentalT-Lymphocytes, Helper-InducerInterleukinsLipopolysaccharidesMice, Inbred C57BLMycobacterium tuberculosisReceptors, Thyroid HormoneAutoimmunityT-Lymphocyte SubsetsReceptors, Antigen, T-Cell, gamma-deltaCD3 Complex
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Interleukin-1 and IL-23 Induce Innate IL-17 Production from γδ T Cells, Amplifying Th17 Responses and Autoimmunity · Scinovex