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Interleukin 17–producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages

Nature Immunology · 2005 · Vol. 6(11) · pp. 1123–1132
Laurie E. HarringtonRobin D. HattonPaul R. ManganHenrietta TurnerTheresa L. MurphyKenneth M. MurphyCasey T. Weaver
T-cell and B-cell ImmunologyPsoriasis: Treatment and PathogenesisImmune Cell Function and InteractionEffectorSTAT4BiologyAutoimmunityInterleukin 23Interleukin 21ImmunologyCell biologyT helper cellInterleukin 3

MeSH terms

T-bet Transcription FactorAnimalsDNA-Binding ProteinsT-Lymphocytes, Helper-InducerInterferon Type IInterferon-gammaInterleukinsMice, Mutant StrainsTranscription FactorsTrans-ActivatorsCD4 AntigensTh1 CellsTh2 CellsCell LineageInterleukin-17
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Interleukin 17–producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages · Scinovex