article Open AccessTop 1% cited
Defining Molecular Cornerstones during Fibroblast to iPS Cell Reprogramming in Mouse
Cell stem cell · 2008 · Vol. 2(3) · pp. 230–240
Matthias Stadtfeld(Massachusetts General Hospital)Nimet Maherali(Harvard Stem Cell Institute)David T. Breault(Boston Children's Hospital)Konrad Hochedlinger✉(Harvard Stem Cell Institute)
Pluripotent Stem Cells ResearchCRISPR and Genetic EngineeringRenal and related cancersReprogrammingBiologySOX2Induced pluripotent stem cellKLF4Cell biologyDownregulation and upregulationHomeobox protein NANOGEmbryonic stem cellStem cell
MeSH terms
Genetic VectorsMice, TransgenicTime FactorsFibroblastsKruppel-Like Factor 4AnimalsCells, CulturedFemaleTranscription FactorsX ChromosomeLewis X AntigenThy-1 AntigensTelomerasePluripotent Stem CellsMice
Funding
- National Institutes of Health
Citations
824
FWCI
39.72
field-weighted impact
References
38
Percentile
100%
vs. same field & year
Citations per year
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References
Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts
Nature Biotechnology · 2007 · 2,767 citations
Directly Reprogrammed Fibroblasts Show Global Epigenetic Remodeling and Widespread Tissue Contribution
Cell stem cell · 2007 · 1,716 citations
DNA Methyltransferases Dnmt3a and Dnmt3b Are Essential for De Novo Methylation and Mammalian Development
Cell · 1999 · 6,039 citations
Strategies and New Developments in the Generation of Patient-Specific Pluripotent Stem Cells
Cell stem cell · 2007 · 738 citations
Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors
Cell · 2006 · 26,294 citations
Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors
Cell · 2007 · 20,020 citations
Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells
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