article Open AccessTop 1% cited
Directly Reprogrammed Fibroblasts Show Global Epigenetic Remodeling and Widespread Tissue Contribution
Cell stem cell · 2007 · Vol. 1(1) · pp. 55–70
Nimet Maherali✉(Harvard University)Rupa Sridharan(UCLA Jonsson Comprehensive Cancer Center)Wei Xie(UCLA Jonsson Comprehensive Cancer Center)Jochen Utikal(Massachusetts General Hospital)Sarah Eminli(Massachusetts General Hospital)Katrin Arnold(Massachusetts General Hospital)Matthias Stadtfeld(Massachusetts General Hospital)Robin Yachechko(UCLA Jonsson Comprehensive Cancer Center)Jason Tchieu(UCLA Jonsson Comprehensive Cancer Center)Rudolf Jaenisch(Whitehead Institute for Biomedical Research)Kathrin Plath(Johnson & Johnson (United States))Konrad Hochedlinger(Massachusetts General Hospital)
Pluripotent Stem Cells ResearchCRISPR and Genetic EngineeringRenal and related cancersReprogrammingBiologyInduced pluripotent stem cellEpigeneticsKLF4EpigenomeSOX2Somatic cellEmbryonic stem cellCell biology
MeSH terms
Kruppel-Like Factor 4AnimalsCell DifferentiationFemaleFibroblastsTranscription FactorsDNA MethylationReverse Transcriptase Polymerase Chain ReactionNanotechnologyEpigenesis, GeneticX Chromosome InactivationMice
Funding
- Leukemia and Lymphoma Society
- Harvard Stem Cell Institute
Citations
1,716
FWCI
82.70
field-weighted impact
References
36
Percentile
100%
vs. same field & year
Citations per year
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References
Nuclear reprogramming of somatic cells by in vitro hybridization with ES cells
Current Biology · 2001 · 868 citations
Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability
Genes & Development · 2000 · 1,414 citations
Early Lineage Segregation between Epiblast and Primitive Endoderm in Mouse Blastocysts through the Grb2-MAPK Pathway
Developmental Cell · 2006 · 913 citations
Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors
Cell · 2006 · 26,294 citations
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