article Open AccessTop 1% cited
Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors
Cell · 2006 · Vol. 126(4) · pp. 663–676
Kazutoshi Takahashi(Kyoto University)Shinya Yamanaka✉(Japan Science and Technology Agency)
Pluripotent Stem Cells ResearchCRISPR and Genetic EngineeringRenal and related cancersHomeobox protein NANOGBiologySOX2Embryonic stem cellInduced pluripotent stem cellReprogrammingKOSRCell biologyStem cellEmbryoid body
MeSH terms
Nanog Homeobox ProteinKruppel-Like Factor 4AdultAnimalsCell DifferentiationCells, CulturedDNA-Binding ProteinsEmbryo, MammalianFibroblastsHumansMice, NudeMice, TransgenicTrans-ActivatorsProto-Oncogene Proteins c-mycCell Transplantation
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236.06
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51
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References
Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells
Nature Genetics · 2000 · 3,587 citations
Isolation and Characterization of Multipotent Skin‐Derived Precursors from Human Skin
Stem Cells · 2005 · 675 citations
Suppression of SHP-2 and ERK Signalling Promotes Self-Renewal of Mouse Embryonic Stem Cells
Developmental Biology · 1999 · 570 citations
Establishment in culture of pluripotential cells from mouse embryos
Nature · 1981 · 8,538 citations
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Gene · 1991 · 5,175 citations
Nuclear reprogramming of somatic cells by in vitro hybridization with ES cells
Current Biology · 2001 · 868 citations
Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells.
Proceedings of the National Academy of Sciences · 1981 · 5,698 citations
Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3
Genes & Development · 1998 · 1,530 citations
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