article Open AccessTop 1% cited
Stage-Specific Optimization of Activin/Nodal and BMP Signaling Promotes Cardiac Differentiation of Mouse and Human Pluripotent Stem Cell Lines
Cell stem cell · 2011 · Vol. 8(2) · pp. 228–240
Steven Kattman(University Health Network)Alec Witty(University of Toronto)Mark Gagliardi(University Health Network)Nicole Dubois(University Health Network)Maryam Niapour(University Health Network)Akitsu Hotta(SickKids Foundation)James Ellis(SickKids Foundation)Gordon Keller✉(University Health Network)
Pluripotent Stem Cells ResearchCongenital heart defects researchCRISPR and Genetic EngineeringBiologyMesodermNodal signalingNODALInduced pluripotent stem cellEmbryonic stem cellCell biologyStem cellCellular differentiationActivin receptor
MeSH terms
AnimalsCell DifferentiationFlow CytometryHumansBone Morphogenetic ProteinsReverse Transcriptase Polymerase Chain ReactionActivinsMyocytes, CardiacPluripotent Stem CellsMiceNodal Protein
Funding
- National Institutes of Health
- Canadian Institutes of Health Research
Citations
1,171
FWCI
44.18
field-weighted impact
References
57
Percentile
100%
vs. same field & year
Citations per year
Cited by
Redefining the In Vivo Origin of Metanephric Nephron Progenitors Enables Generation of Complex Kidney Structures from Pluripotent Stem Cells
Cell stem cell · 2013 · 851 citations
Directed cardiomyocyte differentiation from human pluripotent stem cells by modulating Wnt/β-catenin signaling under fully defined conditions
Nature Protocols · 2012 · 1,795 citations
Pluripotent Stem Cell-Based Cell Therapy—Promise and Challenges
Cell stem cell · 2020 · 1,177 citations
References
Multipotent Flk-1+ Cardiovascular Progenitor Cells Give Rise to the Cardiomyocyte, Endothelial, and Vascular Smooth Muscle Lineages
Developmental Cell · 2006 · 727 citations
Defining Molecular Cornerstones during Fibroblast to iPS Cell Reprogramming in Mouse
Cell stem cell · 2008 · 824 citations
SB-431542 Is a Potent and Specific Inhibitor of Transforming Growth Factor-β Superfamily Type I Activin Receptor-Like Kinase (ALK) Receptors ALK4, ALK5, and ALK7
Molecular Pharmacology · 2002 · 1,647 citations
Functional Cardiomyocytes Derived From Human Induced Pluripotent Stem Cells
Circulation Research · 2009 · 1,400 citations
Development of definitive endoderm from embryonic stem cells in culture
Development · 2004 · 830 citations
Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat hearts
Nature Biotechnology · 2007 · 2,204 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.