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The ribosome profiling strategy for monitoring translation in vivo by deep sequencing of ribosome-protected mRNA fragments

Nature Protocols · 2012 · Vol. 7(8) · pp. 1534–1550
Nicholas T. IngoliaGloria A. BrarSilvi RouskinAnna McGeachyJonathan S. Weissman
RNA and protein synthesis mechanismsRNA modifications and cancerRNA Research and SplicingRibosome profilingDeep sequencingRibosomeBiologyComputational biologyTranslation (biology)NucleaseMessenger RNAGeneticsGenome

MeSH terms

AnimalsBase SequenceHarringtoninesHumansMolecular Sequence DataPeptide Chain Initiation, TranslationalRibonucleasesRibosomesRNA, MessengerRNA, RibosomalSaccharomyces cerevisiaeProtein BiosynthesisGene LibrarySequence Analysis, RNATranscriptome
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The ribosome profiling strategy for monitoring translation in vivo by deep sequencing of ribosome-protected mRNA fragments · Scinovex