article Open AccessTop 1% cited
Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis
Nature Cell Biology · 2006 · Vol. 8(10) · pp. 1124–1132
Shída Yousefi✉(University of Bern)Remo Perozzo(University of Geneva)Inès Schmid(University of Bern)Andrew Ziemiecki(University of Bern)Thomas Schaffner(University of Bern)Léonardo Scapozza(University of Geneva)Thomas Brunner(University of Bern)Hans‐Uwe Simon(University of Bern)
Autophagy in Disease and TherapyCalpain Protease Function and RegulationRNA Interference and Gene DeliveryATG5AutophagyCalpainCell biologyApoptosisGene silencingProgrammed cell deathCleavage (geology)BiologySmall interfering RNA
MeSH terms
Autophagy-Related Protein 5Antibiotics, AntineoplasticAntineoplastic Agents, PhytogenicAutophagyCalpainCytosolDoxorubicinEnzyme ActivationEnzyme InhibitorsEtoposideHeLa CellsHumansMicrotubule-Associated ProteinsMitochondriaGranulocyte-Macrophage Colony-Stimulating Factor
Citations
1,272
FWCI
33.56
field-weighted impact
References
35
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100%
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References
Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes
Nature Cell Biology · 2004 · 1,330 citations
Development by Self-Digestion
Developmental Cell · 2004 · 3,629 citations
Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene
Journal of Clinical Investigation · 2003 · 2,194 citations
Automatic and Quantitative Measurement of Protein-Protein Colocalization in Live Cells
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Oncogene · 2004 · 1,376 citations
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Molecular Cell · 2003 · 1,759 citations
Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and Abl.
The Journal of Experimental Medicine · 1995 · 2,850 citations
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