reviewTop 1% cited
Autophagy as a cell death and tumor suppressor mechanism
Oncogene · 2004 · Vol. 23(16) · pp. 2891–2906
Devrim Gözüaçık✉(Weizmann Institute of Science)Adi Kimchi(Weizmann Institute of Science)
Autophagy in Disease and TherapyToxoplasma gondii Research StudiesEndoplasmic Reticulum Stress and DiseaseAutophagyBiologyProgrammed cell deathCell biologyOrganelleMitophagyCellMitochondrionCytoplasmVacuole
MeSH terms
AnimalsAutophagyCell Transformation, NeoplasticHeat-Shock ProteinsHumansLysosomesNeoplasmsOncogenesSignal TransductionEukaryotic Initiation Factor-2ApoptosisCalcium-Calmodulin-Dependent Protein KinasesHSP70 Heat-Shock ProteinsGTP-Binding ProteinsPhosphatidylinositol 3-Kinases
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120
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References
Protection against Fatal Sindbis Virus Encephalitis by Beclin, a Novel Bcl-2-Interacting Protein
Journal of Virology · 1998 · 1,116 citations
Active cell death induced by the anti-estrogens tamoxifen and ICI 164 384 in human mammary carcinoma cells (MCF-7) in culture: the role of autophagy
Carcinogenesis · 1996 · 511 citations
Mouse Apg16L, a novel WD-repeat protein, targets to the autophagic isolation membrane with the Apg12-Apg5 conjugate
Journal of Cell Science · 2003 · 758 citations
The mitochondrial permeability transition in cell death: a common mechanism in necrosis, apoptosis and autophagy
Biochimica et Biophysica Acta (BBA) - Bioenergetics · 1998 · 1,382 citations
TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling
Nature Cell Biology · 2002 · 3,038 citations
Isolation and characterization of autophagy‐defective mutants of <i>Saccharomyces cerevisiae</i>
FEBS Letters · 1993 · 1,727 citations
The Hallmarks of Cancer
Cell · 2000 · 28,385 citations
Cloning and Genomic Organization of Beclin 1, a Candidate Tumor Suppressor Gene on Chromosome 17q21
Genomics · 1999 · 798 citations
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