reviewTop 1% cited
Multidrug resistance mediated by the breast cancer resistance protein BCRP (ABCG2)
Oncogene · 2003 · Vol. 22(47) · pp. 7340–7358
L. Austin Doyle✉(U-M Rogel Cancer Center)Douglas D. Ross(U-M Rogel Cancer Center)
Drug Transport and Resistance MechanismsPharmacological Effects and Toxicity StudiesHIV/AIDS drug development and treatmentAbcg2ATP-binding cassette transporterBiologyMultiple drug resistanceP-glycoproteinMultidrug resistance-associated protein 2PharmacologySulindacMitoxantroneEfflux
MeSH terms
ATP Binding Cassette Transporter, Subfamily G, Member 2AnimalsAntineoplastic AgentsBreast NeoplasmsHumansNeoplasm ProteinsSubstrate SpecificityGene Expression Regulation, NeoplasticDrug Resistance, MultipleATP-Binding Cassette TransportersDrug Resistance, Neoplasm
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References
The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype
Nature Medicine · 2001 · 2,273 citations
The multidrug resistance protein family
Biochimica et Biophysica Acta (BBA) - Biomembranes · 1999 · 650 citations
Localisation of breast cancer resistance protein in microvessel endothelium of human brain
Neuroreport · 2002 · 407 citations
A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants
Biochimica et Biophysica Acta (BBA) - Biomembranes · 1976 · 3,268 citations
From MDR to MXR: new understanding of multidrug resistance systems, their properties and clinical significance
Cellular and Molecular Life Sciences · 2001 · 685 citations
The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools
Nucleic Acids Research · 1997 · 39,127 citations
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