article Open AccessTop 1% cited
Regulation of the HIF-1α Level Is Essential for Hematopoietic Stem Cells
Cell stem cell · 2010 · Vol. 7(3) · pp. 391–402
Keiyo Takubo✉(Keio University)Nobuhito Goda(Waseda University)Wakako Yamada(Keio University)Hirono Iriuchishima(Keio University)Eiji Ikeda(Yamaguchi University)Yoshiaki Kubota(Keio University)Haruko Shima(Keio University)Randall S. Johnson(University of California, San Diego)Atsushi Hirao(Kanazawa University)Makoto Suematsu(Keio University)Toshio Suda✉(Keio University)
Hematopoietic Stem Cell TransplantationCancer, Hypoxia, and MetabolismImmune Cell Function and InteractionBiologyStem cellHaematopoiesisCell cycleCell biologyProgenitor cellBone marrowTransplantationHematopoietic stem cellUbiquitin ligase
MeSH terms
AnimalsHypoxiaBone MarrowCell CountCell CycleHematopoietic Stem CellsHomeostasisBone Marrow TransplantationMice, KnockoutMiceHypoxia-Inducible Factor 1, alpha SubunitStem Cell Niche
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Metabolic Regulation of Hematopoietic Stem Cells in the Hypoxic Niche
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References
Thrombopoietin/MPL Signaling Regulates Hematopoietic Stem Cell Quiescence and Interaction with the Osteoblastic Niche
Cell stem cell · 2007 · 790 citations
Maintenance of the Hematopoietic Stem Cell Pool by CXCL12-CXCR4 Chemokine Signaling in Bone Marrow Stromal Cell Niches
Immunity · 2006 · 2,327 citations
HIF-1alpha is required for solid tumor formation and embryonic vascularization
The EMBO Journal · 1998 · 1,593 citations
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