articleTop 10% cited
TGF-β Induces Foxp3 + T-Regulatory Cells from CD4 + CD25 − Precursors
American Journal of Transplantation · 2004 · Vol. 4(10) · pp. 1614–1627
Shuang Fu✉(Icahn School of Medicine at Mount Sinai)Nan Zhang(Gene Therapy Laboratory)Adam C. Yopp(Gene Therapy Laboratory)Dongmei Chen(Gene Therapy Laboratory)Minwei Mao(Gene Therapy Laboratory)Dan Chen(Gene Therapy Laboratory)Haojiang Zhang(Gene Therapy Laboratory)Yaozhong Ding(Gene Therapy Laboratory)Jonathan S. Bromberg(Gene Therapy Laboratory)
T-cell and B-cell ImmunologyImmune Cell Function and InteractionDiabetes and associated disordersFOXP3IL-2 receptorCD28ImmunologyTransforming growth factor betaMedicineCell biologyRegulatory T cellCancer researchTransplantation
MeSH terms
AnimalsAntibodiesCell DivisionDNA-Binding ProteinsInflammationMaleMice, Inbred BALB CReceptors, Interleukin-2CD4-Positive T-LymphocytesInterleukin-4Transforming Growth Factor betaApoptosisCD28 AntigensMiceForkhead Transcription Factors
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537
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99%
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References
Signaling by intrathymic cytokines, not T cell antigen receptors, specifies CD8 lineage choice and promotes the differentiation of cytotoxic-lineage T cells
Nature Immunology · 2010 · 5,839 citations
Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse
Nature Genetics · 2001 · 2,563 citations
Induction and mechanism of action of transforming growth factor‐β‐secreting Th3 regulatory cells
Immunological Reviews · 2001 · 832 citations
Control of Regulatory T Cell Development by the Transcription Factor <i>Foxp3</i>
Science · 2003 · 8,062 citations
An essential role for Scurfin in CD4+CD25+ T regulatory cells
Nature Immunology · 2003 · 2,816 citations
B7/CD28 Costimulation Is Essential for the Homeostasis of the CD4+CD25+ Immunoregulatory T Cells that Control Autoimmune Diabetes
Immunity · 2000 · 2,031 citations
Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
Nature Immunology · 2003 · 7,605 citations
CD4+CD25+ Immunoregulatory T Cells Suppress Polyclonal T Cell Activation In Vitro by Inhibiting Interleukin 2 Production
The Journal of Experimental Medicine · 1998 · 2,598 citations
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