article Open AccessTop 1% cited
Dysregulation of the expression and secretion of inflammation-related adipokines by hypoxia in human adipocytes
Pflügers Archiv - European Journal of Physiology · 2007 · Vol. 455(3) · pp. 479–492
Bohan Wang✉(University of Liverpool)I. Stuart Wood(University of Liverpool)Paul Trayhurn(University of Liverpool)
Lipid metabolism and disordersAdipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and MetabolismInternal medicineEndocrinologyAdipokineAdiponectinHypoxia (environmental)LeptinInflammationAdipose tissueSecretionResistin
MeSH terms
Angiopoietin-Like Protein 4AdultHypoxiaCell DifferentiationCells, CulturedCobaltFemaleGene Expression RegulationHumansMacrophage Migration-Inhibitory FactorsMiddle AgedInterleukin-6Plasminogen Activator Inhibitor 1AdipocytesIntramolecular Oxidoreductases
Funding
- Biotechnology and Biological Sciences Research Council
Citations
387
FWCI
16.90
field-weighted impact
References
54
Percentile
99%
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References
Inflammation and metabolic disorders
Nature · 2006 · 8,779 citations
Hypoxia-responsive transcription factors
Pflügers Archiv - European Journal of Physiology · 2005 · 469 citations
HIF-1 and mechanisms of hypoxia sensing
Current Opinion in Cell Biology · 2001 · 1,266 citations
Targeting HIF-1 for cancer therapy
Nature reviews. Cancer · 2003 · 6,642 citations
Cellular adaptation to hypoxia: O <sub>2</sub> ‐sensing protein hydroxylases, hypoxia‐inducible transcription factors, and O <sub>2</sub> ‐regulated gene expression
The FASEB Journal · 2002 · 1,122 citations
Minireview: The Adipocyte—At the Crossroads of Energy Homeostasis, Inflammation, and Atherosclerosis
Endocrinology · 2003 · 1,189 citations
Signalling role of adipose tissue: adipokines and inflammation in obesity
Biochemical Society Transactions · 2005 · 584 citations
Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension.
Proceedings of the National Academy of Sciences · 1995 · 6,172 citations
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