reviewTop 1% cited
The role of adipose tissue dysfunction in the pathogenesis of obesity-related insulin resistance
Physiology & Behavior · 2007 · Vol. 94(2) · pp. 206–218
Gijs H. Goossens✉(Maastricht University)
Adipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and MetabolismCardiovascular Disease and AdiposityAdipose tissueAdipokineInsulin resistanceInternal medicineEndocrinologyAdipose tissue macrophagesAdipocyteParacrine signallingBiologyWhite adipose tissue
MeSH terms
Adipose TissueAnimalsHypoxiaEndocrine SystemHumansInflammationInsulin ResistanceObesityAdipocytesCell SizeLipid Metabolism
Citations
586
FWCI
12.15
field-weighted impact
References
230
Percentile
99%
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References
Local and systemic insulin resistance resulting from hepatic activation of IKK-β and NF-κB
Nature Medicine · 2005 · 2,216 citations
Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance.
Journal of Clinical Investigation · 1995 · 3,504 citations
Paradoxical Decrease of an Adipose-Specific Protein, Adiponectin, in Obesity
Biochemical and Biophysical Research Communications · 1999 · 4,845 citations
Relationship between Adipocyte Size and Adipokine Expression and Secretion
The Journal of Clinical Endocrinology & Metabolism · 2006 · 1,274 citations
Circulating levels of MCP-1 and IL-8 are elevated in human obese subjects and associated with obesity-related parameters
International Journal of Obesity · 2006 · 512 citations
Enlarged subcutaneous abdominal adipocyte size, but not obesity itself, predicts Type II diabetes independent of insulin resistance
Diabetologia · 2000 · 788 citations
Obesity is associated with macrophage accumulation in adipose tissue
Journal of Clinical Investigation · 2003 · 8,580 citations
HIF-1 and mechanisms of hypoxia sensing
Current Opinion in Cell Biology · 2001 · 1,266 citations
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