reviewTop 1% cited
A decade of caspases
Oncogene · 2003 · Vol. 22(53) · pp. 8543–8567
Alexei Degterev✉(Harvard University)Michael Boyce(Harvard University)Junying Yuan(Harvard University)
Cell death mechanisms and regulationinterferon and immune responsesPhagocytosis and Immune RegulationCaspaseBiologyApoptosisProteasesIntrinsic apoptosisCell biologyCaspase 2Signal transductionXIAPProgrammed cell death
MeSH terms
Allosteric RegulationAnimalsEnzyme ActivationEnzyme InhibitorsHumansTranscriptional ActivationApoptosisCaspases
Citations
1,091
FWCI
20.50
field-weighted impact
References
305
Percentile
100%
vs. same field & year
Citations per year
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References
Fas triggers an alternative, caspase-8–independent cell death pathway using the kinase RIP as effector molecule
Nature Immunology · 2000 · 1,899 citations
The Inflammasome
Molecular Cell · 2002 · 5,936 citations
Increased Caspase 3 and Bax Immunoreactivity Accompany Nuclear GAPDH Translocation and Neuronal Apoptosis in Parkinson's Disease
Experimental Neurology · 2000 · 406 citations
Mechanisms of Caspase Activation and Inhibition during Apoptosis
Molecular Cell · 2002 · 1,810 citations
Mammalian Caspases: Structure, Activation, Substrates, and Functions During Apoptosis
Annual Review of Biochemistry · 1999 · 2,764 citations
Two CD95 (APO-1/Fas) signaling pathways
The EMBO Journal · 1998 · 2,997 citations
Pro-apoptotic cascade activates BID, which oligomerizes BAK or BAX into pores that result in the release of cytochrome c
Cell Death and Differentiation · 2000 · 1,027 citations
Cleavage of BID by Caspase 8 Mediates the Mitochondrial Damage in the Fas Pathway of Apoptosis
Cell · 1998 · 4,423 citations
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