articleTop 1% cited

Differing modes of tumour cell invasion have distinct requirements for Rho/ROCK signalling and extracellular proteolysis

Nature Cell Biology · 2003 · Vol. 5(8) · pp. 711–719

Erik Sahai✉(Cancer Research UK)Christopher J. Marshall(Cancer Research UK)

Cellular Mechanics and Interactions Cell Adhesion Molecules Research Microtubule and mitosis dynamicsMotilityCell biologyExtracellularActinEzrinProteolysisROCK1CytoskeletonCDC42RHOA

MeSH terms

EzrinCell MovementCollagenCytoskeletal ProteinsDrug CombinationsHumansLamininNeoplasmsPeptide HydrolasesPhosphoproteinsProteoglycansTumor Cells, CulturedSignal TransductionProtein Serine-Threonine KinasesCell Culture Techniques

Funding

Cancer Research Institute
Cancer Research UK

Citations

1,132

FWCI

15.57

field-weighted impact

References

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100%

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Citations per year

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References

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Journal of Cell Science · 2001 · 1,193 citations

Rho GTPases are over-expressed in human tumors

International Journal of Cancer · 1999 · 662 citations

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