article Open AccessTop 1% cited
Gene Mutations in the Succinate Dehydrogenase Subunit SDHB Cause Susceptibility to Familial Pheochromocytoma and to Familial Paraganglioma
The American Journal of Human Genetics · 2001 · Vol. 69(1) · pp. 49–54
Dewi Astuti(University of Birmingham)Farida Latif(University of Birmingham)Ashraf Dallol(University of Birmingham)Patricia L. M. Dahia(Dana-Farber Cancer Institute)Fiona Douglas(Royal Victoria Infirmary)Emad GeorgeFilip Sköldberg(Uppsala University)Eystein S. Husebye(Uppsala University)Charis Eng(The Ohio State University)Eamonn R. Maher✉(University of Birmingham)
Adrenal and Paraganglionic TumorsCancer, Hypoxia, and MetabolismHormonal Regulation and HypertensionSDHDSDHBParagangliomaSDHAPheochromocytomaGermline mutationGermlineGeneticsBiologyCancer research
MeSH terms
Proto-Oncogene MasAmino Acid SequenceBase SequenceDNA Mutational AnalysisFemaleHaplotypesHumansMaleMolecular Sequence DataMutationParagangliomaPedigreePheochromocytomaSuccinate DehydrogenaseSequence Alignment
Funding
- British Heart Foundation
- National Cancer Institute
Citations
1,089
FWCI
34.48
field-weighted impact
References
32
Percentile
100%
vs. same field & year
Citations per year
Cited by
The Warburg effect: 80 years on
Biochemical Society Transactions · 2016 · 501 citations
Pheochromocytoma and Paraganglioma: An Endocrine Society Clinical Practice Guideline
The Journal of Clinical Endocrinology & Metabolism · 2014 · 2,701 citations
Mitochondrial TCA cycle metabolites control physiology and disease
Nature Communications · 2020 · 2,577 citations
The Biology of Cancer: Metabolic Reprogramming Fuels Cell Growth and Proliferation
Cell Metabolism · 2008 · 4,067 citations
The Emerging Hallmarks of Cancer Metabolism
Cell Metabolism · 2016 · 5,806 citations
Mitochondria and cancer
Nature reviews. Cancer · 2012 · 2,376 citations
Accumulation of Krebs cycle intermediates and over-expression of HIF1α in tumours which result from germline FH and SDH mutations
Human Molecular Genetics · 2005 · 844 citations
Succinate, an intermediate in metabolism, signal transduction, ROS, hypoxia, and tumorigenesis
Biochimica et Biophysica Acta (BBA) - Bioenergetics · 2016 · 524 citations
References
Mitochondria and Apoptosis
Science · 1998 · 8,971 citations
Ubiquitination of hypoxia-inducible factor requires direct binding to the β-domain of the von Hippel–Lindau protein
Nature Cell Biology · 2000 · 1,582 citations
Related articles
Gene Mutations in the Succinate Dehydrogenase Subunit SDHB Cause Susceptibility to Familial Pheochromocytoma and to Familial Paraganglioma
The American Journal of Human Genetics · 2001 · 1,089 citations
Citation Network
How this paper connects to the literature. Drag to explore, click any node to open that paper.