review Open AccessTop 1% cited
The Emerging Hallmarks of Cancer Metabolism
Cell Metabolism · 2016 · Vol. 23(1) · pp. 27–47
Natalya N. Pavlova(Memorial Sloan Kettering Cancer Center)Craig B. Thompson✉(Memorial Sloan Kettering Cancer Center)
Cancer, Hypoxia, and MetabolismEpigenetics and DNA MethylationRNA modifications and cancerReprogrammingBiologyCarcinogenesisTumor microenvironmentCancer cellMetabolic pathwayGlycolysisCell biologyMetabolismCancer
MeSH terms
AnimalsAntineoplastic AgentsBiological TransportCell Transformation, NeoplasticEnergy MetabolismHumansMutationNeoplasmsSignal TransductionMetabolic Networks and Pathways
Citations
5,806
FWCI
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References
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References
The Common Feature of Leukemia-Associated IDH1 and IDH2 Mutations Is a Neomorphic Enzyme Activity Converting α-Ketoglutarate to 2-Hydroxyglutarate
Cancer Cell · 2010 · 1,966 citations
Cancer genes and the pathways they control
Nature Medicine · 2004 · 4,243 citations
Gene Mutations in the Succinate Dehydrogenase Subunit SDHB Cause Susceptibility to Familial Pheochromocytoma and to Familial Paraganglioma
The American Journal of Human Genetics · 2001 · 1,089 citations
HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption
Cell Metabolism · 2006 · 2,210 citations
HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia
Cell Metabolism · 2006 · 3,827 citations
The Hallmarks of Cancer
Cell · 2000 · 28,385 citations
Human L-type amino acid transporter 1 (LAT1): characterization of function and expression in tumor cell lines
Biochimica et Biophysica Acta (BBA) - Biomembranes · 2001 · 729 citations
Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth
Nature Medicine · 2011 · 2,230 citations
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