article Open AccessTop 1% cited
Canonical Wnt/β-Catenin Signaling Prevents Osteoblasts from Differentiating into Chondrocytes
Developmental Cell · 2005 · Vol. 8(5) · pp. 727–738
Theo P. Hill✉(Research Institute of Molecular Pathology)Daniela Später(Research Institute of Molecular Pathology)Makoto M. Taketo(Kyoto University)Walter Birchmeier(Max Delbrück Center)Christine Hartmann(Research Institute of Molecular Pathology)
Wnt/β-catenin signaling in development and cancerCancer-related gene regulationConnective tissue disorders researchBiologyWnt signaling pathwayCateninCell biologyBeta-cateninLRP6Signal transduction
MeSH terms
AnimalsCell DifferentiationCytoskeletal ProteinsDNA-Binding ProteinsHigh Mobility Group ProteinsMesodermMice, Mutant StrainsMutationOsteoblastsOsteogenesisTranscription FactorsSignal TransductionTrans-ActivatorsMice, KnockoutGene Expression Regulation, Developmental
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References
The Wnt Antagonist Secreted Frizzled-Related Protein-1 Is a Negative Regulator of Trabecular Bone Formation in Adult Mice
Molecular Endocrinology · 2004 · 443 citations
BMP-2 Controls Alkaline Phosphatase Expression and Osteoblast Mineralization by a Wnt Autocrine Loop
Journal of Bone and Mineral Research · 2003 · 763 citations
Reaching a Genetic and Molecular Understanding of Skeletal Development
Developmental Cell · 2002 · 1,599 citations
Intestinal polyposis in mice with a dominant stable mutation of the beta -catenin gene
The EMBO Journal · 1999 · 1,212 citations
Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation
Genes & Development · 1999 · 1,745 citations
The biology of fracture healing in long bones
Journal of Bone and Joint Surgery - British Volume · 1978 · 1,183 citations
The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of <i>Sox5</i> and <i>Sox6</i>
Genes & Development · 2002 · 1,713 citations
Canonical Wnt Signaling in Differentiated Osteoblasts Controls Osteoclast Differentiation
Developmental Cell · 2005 · 1,545 citations
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