articleTop 10% cited

Dkk1-mediated inhibition of Wnt signaling in bone results in osteopenia

Bone · 2006 · Vol. 39(4) · pp. 754–766

Ji Li(Amgen (United States))Ildiko Sarosi(Amgen (United States))Russell C. Cattley(Amgen (United States))James K. Pretorius(Amgen (United States))Frank Asuncion(Amgen (United States))Mario Grisanti(Amgen (United States))Sean Morony(Amgen (United States))Stephen Adamu(Amgen (United States))Zhaopo Geng(Amgen (United States))Wanrong Qiu(Amgen (United States))Paul J. Kostenuik(Amgen (United States))David L. Lacey(Amgen (United States))W. Scott Simonet(Amgen (United States))Brad Bolon(NewPath Research)Xueming Qian(Amgen (United States))Victoria Shalhoub(Amgen (United States))Michael S. Ominsky(Amgen (United States))Hua Zhu Ke(Amgen (United States))Xiaodong Li(Amgen (United States))William G. Richards✉(Amgen (United States))

View via DOI Publisher page

Wnt/β-catenin signaling in development and cancer Muscle Physiology and Disorders Connective tissue disorders researchDKK1OsteoblastOsteopeniaWnt signaling pathwayEndocrinologyInternal medicineLRP5OsteocalcinChemistryOsteoporosis

MeSH terms

AnimalsBone and BonesBone Diseases, MetabolicCells, CulturedEmbryo, MammalianFemaleHumansMaleMice, TransgenicOsteoblastsOsteogenesisPregnancyRecombinant ProteinsSignal TransductionBone Density

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Function and biological roles of the Dickkopf family of Wnt modulators